Uncertainty & Complexity
When Uncertainty is the Data
Once again, the CDC has revised its stance on masks, prompting a barrage of compliments and critiques. But the announcement...
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Predicting COVID-19’s Fall Upswing
The alarm bells have rung, and the alarmists have spoken. COVID-19 is in resurgence. But to predict what this means...
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Of Systems and Attributions
Of all the issues plaguing healthcare, none is more pressing than our inability to see healthcare as a complex system....
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The Fault In Our Letters
The WHO has introduced nomenclature redefining COVID-19 variants to prevent prejudices formed during the pandemic. But a close examination reveals...
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Brave New World
America is the land of optimism, with an undeniable taste for dystopian futures. One which pits technological advancements in medicine...
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Databases for Healthcare Uncertainty
Data drives healthcare, whether it is individual decisions or broader health policies. But data only tells us what we know,...
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What the Indian COVID-19 Crisis Teaches Us – About Ourselves
The country has united in support of India. A unity nowhere to be found during our own COVID-19 crisis, revealing...
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Prospecting for Vaccine Complications
Recently the Johnson & Johnson vaccine was placed on hold. We studied data to compare the risk of blood clots...
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War Elephants of Healthcare
The original battle tanks of antiquity, war elephants were famed for the terror they inflicted on the battlefield. And equally...
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Healthcare is a System
An obvious statement that most would agree with. Yet few understand systemic thinking in healthcare, which requires an understanding of...
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COVID-19’s ‘Miracle’ Drugs
Another day, another miracle drug. Or so it seems. As seemingly every day we hear about new drugs touted as...
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Echo Chambers in Healthcare
Our senses are our world. So what we perceive is what we believe. With the perceptions gleaned during a patient...
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Glucagon-Like Peptide–Based Therapies and Longevity: Clinical Implications from Emerging Evidence
Glucagon-like peptide–based therapies are increasingly used for weight management and glycemic control, but their potential impact on long-term survival remains uncertain. The clinical question addressed in this report is whether treatment with glucagon-like peptide receptor agonists is associated with reductions in all-cause mortality and age-related morbidity beyond their established metabolic effects. This question matters because these agents are now prescribed across broad patient populations, including individuals without diabetes, and long-term exposure may influence cardiovascular, oncologic, and neurodegenerative outcomes. Understanding whether...
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