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The 1 in 10 Physicians With Reservations about Vaccines could be Undermining the Fight Against COVID-19

The Conversation by The Conversation
April 3, 2024
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The 1 in 10 Physicians With Reservations about Vaccines could be Undermining the Fight Against COVID-19

Young female doctor with protective face mask on holding syringe and gesturing like she is against vaccination. Corona virus outbreak concept.

The 1 in 10 U.S. doctors with reservations about vaccines could be undermining the fight against COVID-19

U.S. doctors
While the vast majority of primary care providers have higher confidence in vaccines than the general public, some do not.
Evgeniy Shkolenko/iStock via Getty Images Plus

Matt Motta, Oklahoma State University and Timothy Callaghan, Texas A&M University

American attitudes toward scientific expertise have become increasingly contentious in recent years. But many people across the political spectrum still place high levels of trust in their personal physicians. Correspondingly, both popular media and public health officials have encouraged physicians to serve as strong advocates for COVID-19 vaccination.

At the same time, however, there have been several cases of doctors expressing skepticism about vaccines in the media. Though the American Medical Association found that 96% of physicians reported being fully vaccinated against COVID-19 in June 2021, some high-profile physicians have spread misinformation about vaccine safety. Some patients have also reported that their personal physicians discouraged them from getting vaccinated on both medical and non-medical grounds.

One conservative group of doctors called the American Association of Physicians and Surgeons, which counts Republican Senator and ophthalmologist Rand Paul among its members, offers several examples of how some physicians actively promote vaccine skepticism.

Following the 2015 Disneyland measles outbreak, AAPS shared a press release falsely linking the measles, mumps and rubella vaccine to autism in children, a claim based on fraudulent research that the scientific community has widely discredited. The group has also taken legal action to encourage parental noncompliance with childhood vaccine mandates, using misinterpreted data to suggest that COVID-19 vaccines are uniquely dangerous compared to other vaccines.

While groups like AAPS do not represent the views of most physicians, these examples raise an important question: Just how prevalent is physician vaccine hesitancy, and why might some physicians hold negative views toward vaccines?

As political science and health policy researchers studying vaccine hesitancy, we wanted to answer this question. Our recent study found that the same factors thought to encourage hesitancy in the general public – like having right-leaning political views – might also motivate physician opposition to vaccination.

Physician vaccine confidence is a mixed bag

In May 2021, we asked 625 primary care physicians nationwide about their general attitudes toward vaccines and whether they believed vaccines are safe, effective and important. We also asked PCPs how much confidence they had in the safety of the Moderna, Pfizer-BioNTech and Johnson & Johnson COVID-19 vaccines, which were each authorized for emergency use in the U.S. at the time. Respondents answered these questions on a scale ranging from “strongly agree” to “strongly disagree.”

We also surveyed potential factors that could influence physician attitudes toward vaccines. These included political ideology, previous infection with COVID-19, religiosity and standard demographics like gender, race, ethnicity and income.

On the surface, our results provide some reassuring news for using physicians as leading vaccine promoters. We found that only 5.2% of PCPs were unvaccinated against COVID at the time of our survey, echoing the findings of the American Medical Association’s June 2021 survey. In addition, our results suggest that PCPs’ views toward vaccines are overwhelmingly positive – 88% of physicians agreed or strongly agreed that vaccines in general are safe. Likewise, 90% of physicians agreed that vaccines are effective, and 89% agreed that vaccines are important. When we compared our PCP responses to responses from the general public on the same questions, we found that PCPs are 19% more likely to strongly agree that vaccines are safe and 16% more likely to strongly agree they’re effective.

Digging deeper into the data, however, reveals some troubling trends. Even if most physicians are well-positioned to serve as vaccination advocates, our results still suggest that 10.1% of PCPs do not agree that vaccines in general are safe. Similarly, 9.3% do not agree that all vaccines are effective, and 8.3% do not agree that they are important.

PCP political leanings and previous health experiences may help explain why some hold negative views toward vaccination. We found that politically conservative PCPs and those who previously contracted COVID-19 were 19% less likely to believe that vaccines in general are safe and effective.

We found similar results when examining confidence in the three COVID-19 vaccines available in the U.S. at the time, a little over six months after the first vaccine was authorized. Approximately 90% of PCPs were either “very confident” or “confident” in the safety of the Pfizer-BioNTech and Moderna vaccines. Still, 9.5% and 8.7% lacked confidence in the safety of the Moderna and Pfizer-BioNTech vaccines, respectively. Only 68% of physicians expressed confidence in the Johnson & Johnson vaccine, likely due to reports of its relatively lesser effectiveness at the time.

Health care provider administering vaccine to another health care provider
According to an American Medical Association survey, 96% of physicians were fully vaccinated against COVID-19 in June 2021.
Juanmonino/E+ via Getty Images

Why this matters

Our research finds that physician vaccine hesitancy is more prevalent than vaccination campaigns may have assumed. Vaccine hesitancy among physicians is also likely motivated by the same factors that encourage hesitancy in the general public. This potentially poses a problem for vaccination efforts that rely on physicians to promote vaccine uptake.

[Over 150,000 readers rely on The Conversation’s newsletters to understand the world. Sign up today.]

Nevertheless, our work offers room for potential optimism and ways to improve vaccine confidence in this group.

Partisanship, for example, plays an important role in shaping vaccine hesitancy. Consequently, tactics shown to improve vaccine attitudes in the general public – such as highlighting GOP politicians with more positive views toward vaccination – could potentially increase support for vaccination among physicians as well. In our view, studying ways to encourage vaccine enthusiasm among PCPs could help “move the needle” on vaccine uptake in the U.S.

Matt Motta, Assistant Professor of Political Science, Oklahoma State University and Timothy Callaghan, Assistant Professor of Health Policy and Managment, School of Public Health, Texas A&M University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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An in-depth exploration of drug pricing, including key databases like NADAC, WAC, and ASP, and how they influence the pharmaceutical supply chain, policy, and patient advocacy. The episode also introduces MedPricer's innovative pricing intelligence platform, offering valuable insights for healthcare professionals, policymakers, and patients.

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00:00 Understanding Drug Pricing Dynamics
03:52 Exploring the Drug Pricing Database
10:07 Patient Advocacy and Drug Pricing
13:56 Market Intelligence in Drug Pricing
How NADAC, WAC, and ASP Shape Drug CostsDaily Remedy
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Policy Shift in Peptide Regulation

Clinical Reads

FDA Evaluation of Certain Bulk Drug Substances in Compounding: Clinical Interpretation

FDA Evaluation of Certain Bulk Drug Substances in Compounding: Clinical Interpretation

by Daily Remedy
April 19, 2026
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Clinicians increasingly encounter patients using or requesting peptide-based therapies sourced through compounding pharmacies. The U.S. Food and Drug Administration has identified a subset of bulk drug substances, including certain peptides, that may present significant safety risks when used in compounded formulations. The clinical question is whether these regulatory signals reflect meaningful patient-level risk and how they should influence prescribing behavior. This matters because compounded peptides often sit outside traditional approval pathways, creating uncertainty around quality, dosing consistency, and safety. Understanding...

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