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Home Uncertainty & Complexity

Healthcare’s Problem With Logic

Daily Remedy by Daily Remedy
June 13, 2022
in Uncertainty & Complexity
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Healthcare's Problem With Logic

Healthcare has a problem with logic. Namely, we choose not to use it.

Instead, we substitute intuition for logic and assume the two to be the same. Sometimes we get away with it. Healthcare is experiential enough to where intuition works just enough times to seem like the right way of thinking. Until we realize that using our intuition, our gut-feeling, can lead us astray.

Take the raging debate over the opioid epidemic. The narrative that opioid abuse began with prescription opioids has led to a slew of policies designed to curb prescription opioids. We now know the unintended consequences of such Draconian policies. We see the outcomes, but we never question the logic that led us there.

Likely because we did not use any logic, we used intuition. Intuitively, it makes sense that prescription opioids would lead to opioid overdoses. It just feels right that overprescribing leads to more overdoses. After all, if one goes up, should not the other?

When we see only the outcomes, we create knee-jerk responses to what we see, and we default to our internal Ockham’s razor, the simplest explanation. This is as clear an example of intuition in action as there is.

But there comes a point where intuition becomes bias, and gut-feeling becomes preconceived notions hindering new information. We have long passed that point on opioids. It is time we regain some semblance of logic on the issue.

Forego the tendency to moralize behavior in abstract binary concepts of right or wrong, and look at behavior logically, as behavioral economists and policy wonks do, as an opportunity cost. Behavior in general is most logically understood this way, and patient behavior is no different.

You cannot encourage a diabetic to eat more healthily by taking away all sweets. But you can incrementally lower the intake of high processed carbohydrates. These improvements are usually the most effective, in medicine and in life.

This is the difference between logic and intuition. Logic focuses on the process, the steps along the way. Intuition focuses on the outcome. When the two align, we use our intuition to justify the logic. But when our logic does not align with our intuition, we ignore the logic.

This is why we struggle to create effective health policy and we unveil health laws that cause more harm than good. We emphasize intuition far too much because in healthcare, we rely on data, which is notoriously outcome-based. And when logic conflicts with intuition, we find any reason to dismiss the logic, regardless of how unsound the data may prove.

This is how we get narratives like the one claiming physicians were misled by pharmaceutical companies. We emphasize the outcomes and we ignore the logic that led us there.

This is not to discount the importance of intuition. Indeed, it has worked wonders in medicine. Many crucial discoveries were made through intuition. The progenitor of Genetics, the monk Gregor Mendel, used intuition to calculate the ratios of autosomal dominance in hereditary patterns.

But Genetics today has evolved beyond the days of religious asceticism. It is now one of the most technologically advanced fields in all of healthcare. Intuition continues to play a role, no doubt, but a limited one at that. Instead, logic reigns supreme.

Similarly, in health policy, we must prioritize logical thinking. Study the processes that lead to certain outcomes more than the outcomes themselves.

We would do more for a diabetic by monitoring their daily food intake instead of retroactively adjusting their medications after three months of unchecked dieting. Our intuition tells us to adjust the medications after reviewing the blood work. Our logic tells us to monitor the diet on a day by day basis.

This is the difference between the two. One is proactive and the other is reactive.

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Daily Remedy

Dr. Jay K Joshi serves as the editor-in-chief of Daily Remedy. He is a serial entrepreneur and sought after thought-leader for matters related to healthcare innovation and medical jurisprudence. He has published articles on a variety of healthcare topics in both peer-reviewed journals and trade publications. His legal writings include amicus curiae briefs prepared for prominent federal healthcare cases.

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Videos

This conversation focuses on debunking myths surrounding GLP-1 medications, particularly the misinformation about their association with pancreatic cancer. The speaker emphasizes the importance of understanding clinical study designs, especially the distinction between observational studies and randomized controlled trials. The discussion highlights the need for patients to critically evaluate the sources of information regarding medication side effects and to empower themselves in their healthcare decisions.

Takeaways
GLP-1 medications are not linked to pancreatic cancer.
Peer-reviewed studies debunk misinformation about GLP-1s.
Anecdotal evidence is not reliable for general conclusions.
Observational studies have limitations in generalizability.
Understanding study design is crucial for evaluating claims.
Symptoms should be discussed in the context of clinical conditions.
Not all side effects reported are relevant to every patient.
Observational studies can provide valuable insights but are context-specific.
Patients should critically assess the relevance of studies to their own experiences.
Engagement in discussions about specific studies can enhance understanding

Chapters
00:00
Debunking GLP-1 Medication Myths
02:56
Understanding Clinical Study Designs
05:54
The Role of Observational Studies in Healthcare
Debunking Myths About GLP-1 Medications
YouTube Video DM9Do_V6_sU
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BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us

BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us

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Can lowering tau biology translate into a clinically meaningful slowing of decline in people with early symptomatic Alzheimer’s disease? That is the practical question behind BIIB080, an intrathecal antisense therapy designed to reduce production of tau protein by targeting the tau gene transcript. In a phase 1b program originally designed for safety and dosing, investigators later examined cognitive, functional, and global outcomes as exploratory endpoints. The clinical question matters because current disease-modifying options primarily target amyloid, while tau pathology tracks...

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