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Vaccine Hesitancy is Complicating Physicians’ Obligation to Respect Patient Autonomy

The Conversation by The Conversation
April 3, 2024
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Vaccine Hesitancy is Complicating Physicians’ Obligation to Respect Patient Autonomy

Vaccine hesitancy is complicating physicians’ obligation to respect patient autonomy during the COVID-19 pandemic

patient consulting with Dr.
Over the past couple of decades there has been a shift away from upholding patient autonomy to prioritizing public health.
Terry Vine/DigitalVision via Getty Images

Ryan Liu, Penn State

Sitting barely 6 feet away from me, my patient yelled angrily, his face mask slipping to his upper lip: “No, I will not get vaccinated. And nothing you do or say will change that fact.” He provided no reason for why he was so opposed to the COVID-19 vaccine.

As a primary care resident physician working in an underserved area of Reading, Pennsylvania, I have seen patients of all age groups refusing to follow COVID-19 guidelines such as wearing a mask, social distancing or getting the vaccine.

Exposure in health care settings has accounted for a large number of infections. Early on in the pandemic, health care workers and their household members accounted for 1 in 6 patients ages 18 to 65 admitted to the hospital with COVID-19. Vaccines reduced that risk considerably, and by August 2021, the risk of infection to health care workers had been cut by two-thirds. According to the Centers for Disease Control and Prevention, less than 70% of the vaccine-eligible U.S. population is fully vaccinated, not accounting for the booster, although these numbers are changing.

When a patient refuses to get the vaccine, a health care worker usually gets involved to counsel that patient. This may take a considerable amount of time, and unfortunately, the results may not always be favorable. Many in the medical community believe that the onus is on the patient to get vaccinated, and if they do not do so, they should be seen as culpable for contracting COVID-19. One such example is the case being made to give lower priority for organ transplants to those willfully unvaccinated.

As new variants of COVID-19 emerge and pose threats to everyone’s health, doctors are struggling with their obligation to “do no harm” and their obligation to respect patient autonomy. Some wonder whether the two might even conflict with each other.

‘Do no harm’

A young woman getting a vaccine shot on her upper arm.
Doctors are concerned that unvaccinated people might pose a risk to others.
Andriy Onufriyenko/Moment via Getty Images

People who refuse to get vaccinated put the lives of doctors and nurses at risk. They also negatively affect the outcomes of other patients. Whether or not this is done with malicious intent, this refusal is a disregard for human lives. As much as physicians are directed to “do no harm” to the patient, they must also “do no harm” to everyone else.

Physicians respect the patient’s right to refuse treatment for their own illness, but may find it difficult to respect the patient’s right to refuse treatment for a contagious disease that can affect everyone else.

Ethical theories may help provide an understanding of the physician’s duties.

German philosopher Immanuel Kant developed the concept of an absolute, universal reason to act from duty. In this theory, it would appear that educating patients to get vaccinated is not just something physicians have the option to do, but something they have a moral duty to do.

While doctors cannot force the patient to get vaccinated out of respect for the patient’s ability to make informed decisions, doctors have a duty to educate their patients on COVID-19, the vaccine and the importance of protecting other patients and the general public.

Autonomy of patients

This also raises an important issue of patient autonomy. Autonomy is one of the pillars of bioethics, and it is the notion that the patient has the ultimate decision-making power. There is no denying that a patient’s decision-making responsibility is important. After all, patients want the best for themselves, and respecting their decisions is respecting their well-being.

[3 media outlets, 1 religion newsletter. Get stories from The Conversation, AP and RNS.]

However, some scholars are also discussing the idea that the doctor knows best. This concept, known as “paternalism,” is the idea that physicians ought to be the ones to ultimately make the decision for what is ethically right for the patient, as physicians know better. One example would be using soft materials to restrain the hands of an intubated COVID-19 patient if they become agitated and try to remove their breathing tube.

Just last year, some doctors made the case to mandate COVID-19 vaccinations for health care workers. This argument from doctors inevitably gets pushback from those who are anti-mandate, and the discord further divides the patient from the physician.

Scarce resources

Then there is the issue of who should get scarce lifesaving treatments: one who has been vaccinated or one who has refused the vaccine?

One example of this issue is the use of Paxlovid, a relatively new medication that can be prescribed in the outpatient setting for the treatment of COVID-19. The clinical trials initially treated those who were unvaccinated. Based on those studies, the pharmaceutical company Pfizer claims that Paxlovid is 89% effective in reducing the risk of hospitalization or death among study participants receiving treatment within three days of symptom onset. If there is one lifesaving medicine and two patients – one with breakthrough COVID-19 and one refusing to be vaccinated – which one should doctors prioritize?

There are other ethical implications from an insurance standpoint, in terms of who should bear the cost and whether the unvaccinated should pay a higher premium.

In my personal practice, I have been successful in changing people’s minds about the vaccine through education and counseling. But what patient autonomy should look like as we learn to live with COVID-19 and how the doctor-patient relationship might change are questions left unanswered. The conversations on these bigger issues are just getting started.

Ryan Liu, Family Medicine Resident Physician, Penn State

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Videos

This conversation focuses on debunking myths surrounding GLP-1 medications, particularly the misinformation about their association with pancreatic cancer. The speaker emphasizes the importance of understanding clinical study designs, especially the distinction between observational studies and randomized controlled trials. The discussion highlights the need for patients to critically evaluate the sources of information regarding medication side effects and to empower themselves in their healthcare decisions.

Takeaways
GLP-1 medications are not linked to pancreatic cancer.
Peer-reviewed studies debunk misinformation about GLP-1s.
Anecdotal evidence is not reliable for general conclusions.
Observational studies have limitations in generalizability.
Understanding study design is crucial for evaluating claims.
Symptoms should be discussed in the context of clinical conditions.
Not all side effects reported are relevant to every patient.
Observational studies can provide valuable insights but are context-specific.
Patients should critically assess the relevance of studies to their own experiences.
Engagement in discussions about specific studies can enhance understanding

Chapters
00:00
Debunking GLP-1 Medication Myths
02:56
Understanding Clinical Study Designs
05:54
The Role of Observational Studies in Healthcare
Debunking Myths About GLP-1 Medications
YouTube Video DM9Do_V6_sU
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Clinical Reads

BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us

BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us

by Daily Remedy
February 15, 2026
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Can lowering tau biology translate into a clinically meaningful slowing of decline in people with early symptomatic Alzheimer’s disease? That is the practical question behind BIIB080, an intrathecal antisense therapy designed to reduce production of tau protein by targeting the tau gene transcript. In a phase 1b program originally designed for safety and dosing, investigators later examined cognitive, functional, and global outcomes as exploratory endpoints. The clinical question matters because current disease-modifying options primarily target amyloid, while tau pathology tracks...

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