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Home Trends

The Despair Epidemic

Daily Remedy by Daily Remedy
August 9, 2021
in Trends
0

The symbol is a semicolon, meaning the sentence could have ended, but did not.

The semicolon is the universal symbol for suicide prevention, symbolizing the fight against a glaring medical epidemic hiding in plain sight for all of America to see. Perhaps we choose not to acknowledge it, or choose to fixate on more pressing medical issues, like the COVID-19 pandemic.

But the death toll from suicide is undeniable, and must be acknowledged, indeed confronted, as a public health crisis. The numbers are staggering.

According to the Centers for Disease Control and Prevention (CDC), suicide rates increased by 33% from 1999 to 2019, but decreased by 5.6% in 2020, presumably a victory in our efforts to curtail suicide in our communities.

But the numbers do not reveal the full extent of the problem. Drug overdoses and alcoholism related mortality are tallied separately from suicides, and the two forms of mortality spiked in 2020, the same year suicide rates decreased.

Policy advocates now suggest that we should lump overdoses and suicides into one category, dubiously termed deaths of despair, in order to properly understand the magnitude of this hiding-in-plain-sight epidemic gripping the country.

But the more broadly we define it, the more ambiguous the term becomes. What exactly is death of despair? Should we categorize the death by malnutrition in a ninety year old widower, abandoned to an equally decrepit nursing home, along the same lines as the death of an unemployed steel worker, who died from complications stemming from alcohol induced cirrhosis at age forty?

Even the most generous of healthcare policy wonks would find that overly-broad, and rightfully so. Both are technically deaths of despair, in which a perpetual sadness, whether we formalize it as depression or allow it to be more subtly understood, influenced the clinical outcome. But the outcome is all that the two have in common.

The series of patient decisions and the circumstances in which those decisions were made are different, and should be categorized differently. But among deaths generally accepted to be deaths of despair – suicides, overdoses, and substance abuse – we find similar patterns of decisions and circumstances.

And it is through these decisions and circumstances we should understand and frame deaths of despair – as each patient death, though disparate and unique, can be defined by a similar patterns of behavior that led to the eventual outcome.

This requires us to understand healthcare outside of the traditional context of medicine, and more as a social construct, something espoused by the existentialist philosophers of the early twentieth century. Writers such as Sartre and Camus envisioned an irrational world, defined by the lack of logic and the absurdity of individuals trying to navigate through a fundamentally flawed society.

They wrote of men and women fighting against an unjust system, choosing between a life of desensitized conformity or of self-sacrificing defiance, only to find both courses equally imperfect – a situation many across the country currently find themselves.

Psychiatrist, and Holocaust survivor, Dr. Victor Frankl attempted to integrate these philosophical beliefs into healthcare, formalizing it into a medical condition called noesis. In modern healthcare, we understand all of this to fit under the broad umbrella of mental health, and offer patients diagnosed with certain psychiatric disorders an ever expanding array of clinical services, such as tele-psychiatric care or social media forums focused on mental health, a digital version of group therapy.

But these broad categorizations again miss the mark. A mental health crisis, and the decision to inflict self-harm, is not a static state of mind, or a fixed diagnosis, and certainly encompasses far more than a defined set of psychiatric disorders.

It is a dynamic series of decisions within a changing set of circumstances, always in flux, never confined to any one definition.

Instead, we should visualize mental health as a dynamic series of decisions, and study those decisions over the course of a person’s life, under changing circumstances.

By categorizing a person to a mental health condition or to an outcome, we define that person through a conceptual framework. But in defining, we often limit our understanding of what is truly afflicting that person.

Mental health cannot be fully understood through limiting definitions, it is an ongoing process, like a sentence punctuated not by a period, but by a semicolon, forever continuing, changing along decisions made through changing circumstances.

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Daily Remedy

Dr. Jay K Joshi serves as the editor-in-chief of Daily Remedy. He is a serial entrepreneur and sought after thought-leader for matters related to healthcare innovation and medical jurisprudence. He has published articles on a variety of healthcare topics in both peer-reviewed journals and trade publications. His legal writings include amicus curiae briefs prepared for prominent federal healthcare cases.

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Videos

Most employers are unknowingly steering their health plans toward higher costs and reduced control — until they understand how fiduciary missteps and anti-competitive contracts bleed their budgets dry. Katie Talento, a recognized health policy leader, reveals how shifting the network paradigm can save millions by emphasizing independent providers, direct contracting, and innovative tiering models.

Grounded in real-world case studies like Harris Rosen’s community-driven initiative, this episode dives deep into practical strategies to realign incentives—focusing on primary care, specialty care, and transparent vendor relationships. You'll discover how traditional carrier networks are often Trojan horses, locking employers into costly, opaque arrangements that undermine fiduciary duties. Katie breaks down simple yet powerful reforms: owning your data, eliminating conflicts of interest, and outlawing anti-competitive contract clauses.

We explore how a post-network framework—where patients are free to choose providers without restrictive network barriers—can massively reduce costs and improve health outcomes. You'll learn why independent, locally owned providers are vital to rebuilding trust, reducing unnecessary procedures, and reinvesting savings into the community. This conversation offers clarity on the unseen legal landmines employers face and actionable ways to craft health plans built on transparency, independence, and aligned incentives.

Perfect for HR pros, benefits advisors, physicians, and employer leaders committed to transforming healthcare from the ground up. If you’re tired of broken healthcare models draining your budget and frustrating your staff, this episode will empower you to take control by understanding and reshaping the very foundations of employer-sponsored health. Discover the blueprint for smarter, fairer, and more sustainable benefits.

Visit katytalento.com or allbetter.health to connect directly and explore how these innovations can work for your organization. Your path toward a healthier, more cost-effective future starts here.

Chapters

00:00 Introduction to Employer-Sponsored Health Plans
02:50 Understanding ERISA and Fiduciary Responsibilities
06:08 The Misalignment of Clinical and Financial Interests
08:54 Enforcement and Legal Implications for Employers
11:49 Redefining Networks: The Post-Network Framework
25:34 Navigating Healthcare Contracts and Cash Payments
27:31 Understanding Employer Health Plan Structures
28:04 The Role of Benefits Advisors in Health Plans
30:45 Governance and Data Ownership in Health Plans
37:05 Case Study: The Rosen Hotels' Health Model
41:33 Incentivizing Healthy Choices in Healthcare
47:22 Empowering Primary Care and Independent Providers
The Hidden Costs Employers Don’t See in Traditional Health Plans
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Policy Shift in Peptide Regulation

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Semaglutide and the Expansion Problem: When One Trial Becomes a Platform

Semaglutide and the Expansion Problem: When One Trial Becomes a Platform

by Daily Remedy
March 30, 2026
0

Semaglutide has moved beyond its original indication and now sits at the center of a widening set of clinical questions: cardiovascular risk, kidney disease progression, and even neurodegeneration. The question is no longer whether the drug lowers glucose or reduces weight—it does—but how far those effects extend across systems, and whether evidence from one population can be translated into another without distortion. Large, well-powered trials have produced consistent signals, yet those signals are now being applied in contexts that were...

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