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    Debunking Myths About GLP-1 Medications

    Debunking Myths About GLP-1 Medications

    February 16, 2026
    The Future of LLMs in Healthcare

    The Future of LLMs in Healthcare

    January 26, 2026
    The Future of Healthcare Consumerism

    The Future of Healthcare Consumerism

    January 22, 2026
    Your Body, Your Health Care: A Conversation with Dr. Jeffrey Singer

    Your Body, Your Health Care: A Conversation with Dr. Jeffrey Singer

    July 1, 2025

    The cost structure of hospitals nearly doubles

    July 1, 2025
    Navigating the Medical Licensing Maze

    The Fight Against Healthcare Fraud: Dr. Rafai’s Story

    April 8, 2025
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    How Confident Are You in RFK Jr.’s Health Leadership?

    How Confident Are You in RFK Jr.’s Health Leadership?

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    AI in Healthcare Decision-Making

    February 1, 2026

    Survey Results

    Can you tell when your provider does not trust you?

    Can you tell when your provider does not trust you?

    January 18, 2026
    Do you believe national polls on health issues are accurate

    National health polls: trust in healthcare system accuracy?

    May 8, 2024
    Which health policy issues matter the most to Republican voters in the primaries?

    Which health policy issues matter the most to Republican voters in the primaries?

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Healthcare’s False Starts

Daily Remedy by Daily Remedy
September 6, 2022
in Trends
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Healthcare’s False Starts

Healthcare is mired in a series of false starts. First it was the COVID-19 pandemic, then the vaccine roll-out, and now, the latest is monkey pox. It feels as though healthcare cannot help but get in its way, over and over.

We blame politicians. We blame policy. But in reality, we have no one to blame. These false starts are not some problem plaguing healthcare for which we have to find a solution. Rather, they are a feature.

Healthcare by nature is reactionary. We observe things over time and react to the changes iteratively. Rarely do we preemptively give medication for a disease that we have yet to diagnose. And when we do, we usually have a strong suspicion for what it could be, and we call it empirical treatment.

It is a fancy way of saying we make guesses based on what we see, what our experiences tell us. But this is a tricky game, because appearances can be deceiving, particularly in medicine. An initial presenting diagnosis may look one way, and then change, based on additional information gleaned either through clinical evaluation or additional testing.

Ultimately, it is the constellation of symptoms and signs that determine the diagnosis, which takes time to collect. But in the interval, while waiting for the information to present itself, we hedge toward what we think the diagnosis could be.

We hedge toward what we know. In medicine, this is considered good clinical practice. But nothing in medicine is entirely good or bad. And what can be good in one scenario can be quite the opposite in another. This overreliance on the familiar produces a bias, which we aptly name familiarity bias.

It is one of the most common cognitive biases affecting clinicians. We gravitate toward what we know until what we know becomes all there is to know. It is why patients with rare diseases are misdiagnosed at first. These patients go through a gauntlet of more common diagnoses with more common treatment options, until they all prove to be wrong.

This is familiarity bias manifesting over patient care. Eventually, we arrive at the right diagnosis and provide the correct treatment, but only after iteratively parsing through multiple clinical conditions. It is how healthcare works. It is the scientific method applied to clinical decision-making.

The problem comes when we apply this thinking to health policy. We forget that healthcare is not only a science, but an art as well. Or, as Sir William Osler, the progenitor of modern medicine would say, “a science of uncertainty and an art of probability”.

But we dislike uncertainty in health policy. We like quick fixes. They are politically advantageous and make for better public narratives. Just look at recent history. The first year of the COVID-19 pandemic coincided with the 2020 presidential election. Nothing health policy related was free of political implications. Every COVID projection, data point, or policy had some ramification on the pending election – and politicians distorted all things clinical to be politically favorable.

As a result, we saw a slew of narratives from various policy leaders with overt political agendas. Some decried the pandemic as a hoax, some said it was like a “bad case of the flu”, while others advocated for draconian lockdowns.

In hindsight, none of these narratives were entirely correct. Just like nothing in medicine is entirely correct or incorrect. Healthcare is a complex blend of changing information that dynamically shifts over time.

No single health policy is uniformly right all the time because such a concept does not exist in healthcare. No single narrative can ever be truly right from start to finish. More than anything else, these narratives are first impressions.

They are the initial thoughts a clinician has about a patient diagnosis before all the clinical information has materialized. But unlike clinicians who know they need more information, policy wonks touting these narratives never considered changing their tune as more information trickled in.

They sang the same song regardless of any new information or data. For them, whatever corroborates the initial belief is valid, and whatever refutes it is invalid. Through such thinking, we create selective echo chambers in which people with similar first impressions reiterate their preexisting beliefs, over and over.

But medicine is not designed to be reiterated like this. It is iterative, changing over time as we glean new information. And what is true for the individual patient remains true at the policy level. Only we like to believe it is not. Rather, those at the helm of health policy like to believe it is not.

They would rather stick with erroneous beliefs than admit they are unsure of what to do. So we have with multiple false starts based on incomplete first impressions.

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Daily Remedy

Dr. Jay K Joshi serves as the editor-in-chief of Daily Remedy. He is a serial entrepreneur and sought after thought-leader for matters related to healthcare innovation and medical jurisprudence. He has published articles on a variety of healthcare topics in both peer-reviewed journals and trade publications. His legal writings include amicus curiae briefs prepared for prominent federal healthcare cases.

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Videos

This conversation focuses on debunking myths surrounding GLP-1 medications, particularly the misinformation about their association with pancreatic cancer. The speaker emphasizes the importance of understanding clinical study designs, especially the distinction between observational studies and randomized controlled trials. The discussion highlights the need for patients to critically evaluate the sources of information regarding medication side effects and to empower themselves in their healthcare decisions.

Takeaways
GLP-1 medications are not linked to pancreatic cancer.
Peer-reviewed studies debunk misinformation about GLP-1s.
Anecdotal evidence is not reliable for general conclusions.
Observational studies have limitations in generalizability.
Understanding study design is crucial for evaluating claims.
Symptoms should be discussed in the context of clinical conditions.
Not all side effects reported are relevant to every patient.
Observational studies can provide valuable insights but are context-specific.
Patients should critically assess the relevance of studies to their own experiences.
Engagement in discussions about specific studies can enhance understanding

Chapters
00:00
Debunking GLP-1 Medication Myths
02:56
Understanding Clinical Study Designs
05:54
The Role of Observational Studies in Healthcare
Debunking Myths About GLP-1 Medications
YouTube Video DM9Do_V6_sU
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2027 Medicare Advantage & Part D Advance Notice

Clinical Reads

BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us

BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us

by Daily Remedy
February 15, 2026
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Can lowering tau biology translate into a clinically meaningful slowing of decline in people with early symptomatic Alzheimer’s disease? That is the practical question behind BIIB080, an intrathecal antisense therapy designed to reduce production of tau protein by targeting the tau gene transcript. In a phase 1b program originally designed for safety and dosing, investigators later examined cognitive, functional, and global outcomes as exploratory endpoints. The clinical question matters because current disease-modifying options primarily target amyloid, while tau pathology tracks...

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