Tuesday, January 31, 2023
ISSN 2765-8767
  • Survey
  • Podcast
  • Write for Us
Daily Remedy
  • Home
  • Articles
  • Podcasts
    A conversation with Dr. Selwyn O. Rogers, trauma surgeon and gun policy expert

    A conversation with Dr. Selwyn O. Rogers, trauma surgeon and gun policy expert

    November 25, 2022
    A conversation with Dr. Kyle Fischer, policy director for the Health Alliance for Violence Intervention

    A conversation with Dr. Kyle Fischer, policy director for the Health Alliance for Violence Intervention

    November 25, 2022
    A conversation with Dr. Edwin Leap, physician writer and emergency medicine physician

    A conversation with Dr. Edwin Leap, writer and emergency medicine physician

    November 8, 2022
    A conversation with Mr. Omar M Khateeb, innovator in medical device sales

    A conversation with Mr. Omar M Khateeb, innovator in medical device sales

    October 31, 2022
    A conversation with Miss Smriti Kirubanandan, passionate healthcare strategist

    A conversation with Miss Smriti Kirubanandan, passionate healthcare strategist

    October 23, 2022
    A conversation with Mr. Michael Johnson, legal expert in physician contracts

    A conversation with Mr. Michael Johnson, legal expert in physician contracts

    October 23, 2022
  • Surveys

    Surveys

    Does inflation affect how you use your deductible?

    Does inflation affect how you use your deductible?

    by Jay K Joshi
    December 12, 2022

    Survey Resutls

    How strongly do you believe that you can tell when your provider does not trust you?

    How strongly do you believe that you can tell when your provider does not trust you?

    October 16, 2022
  • About Us
  • Contact us
  • Support Us
No Result
View All Result
  • Home
  • Articles
  • Podcasts
    A conversation with Dr. Selwyn O. Rogers, trauma surgeon and gun policy expert

    A conversation with Dr. Selwyn O. Rogers, trauma surgeon and gun policy expert

    November 25, 2022
    A conversation with Dr. Kyle Fischer, policy director for the Health Alliance for Violence Intervention

    A conversation with Dr. Kyle Fischer, policy director for the Health Alliance for Violence Intervention

    November 25, 2022
    A conversation with Dr. Edwin Leap, physician writer and emergency medicine physician

    A conversation with Dr. Edwin Leap, writer and emergency medicine physician

    November 8, 2022
    A conversation with Mr. Omar M Khateeb, innovator in medical device sales

    A conversation with Mr. Omar M Khateeb, innovator in medical device sales

    October 31, 2022
    A conversation with Miss Smriti Kirubanandan, passionate healthcare strategist

    A conversation with Miss Smriti Kirubanandan, passionate healthcare strategist

    October 23, 2022
    A conversation with Mr. Michael Johnson, legal expert in physician contracts

    A conversation with Mr. Michael Johnson, legal expert in physician contracts

    October 23, 2022
  • Surveys

    Surveys

    Does inflation affect how you use your deductible?

    Does inflation affect how you use your deductible?

    by Jay K Joshi
    December 12, 2022

    Survey Resutls

    How strongly do you believe that you can tell when your provider does not trust you?

    How strongly do you believe that you can tell when your provider does not trust you?

    October 16, 2022
  • About Us
  • Contact us
  • Support Us
No Result
View All Result
Daily Remedy
No Result
View All Result
Home Perspectives

Some Cancers are Preventable with a Vaccine

Jay K Joshi by Jay K Joshi
February 24, 2022
in Perspectives
0
Some Cancers are Preventable with a Vaccine

Ronald C. Desrosiers, University of Miami

One-fifth. Nearly 20% of cancers worldwide are caused by a virus.

These viruses don’t cause cancer until long after they initially infect a person. Rather, the viruses teach the cells they take over how to escape the natural biological process of cell death. This strategy sets these altered cells on a path for other genetic changes that can cause full-blown cancer years down the road.

As a microbiologist and researcher of viruses, I seek to understand how viruses affect living cells and the health of the people who are infected. These particular viruses are unique and interesting, both for their effects on patients and because of the potential ways they might be treated or prevented.

The viral landscape

All known viruses can be categorized into one of 22 distinct families. Five of these families are called “persisting,” because once a person is infected, the virus remains in their body for life. One example is the herpes virus that causes chickenpox in children and can reappear later in life as shingles. This ability to survive over the long term helps the virus spread from person to person.

There are seven known viruses that can cause cancer. Five of them are members of persistent virus families. The human papillomavirus, commonly known as HPV and known to cause cervical cancer, is in the papilloma family. The Epstein-Barr virus, which causes Hodgkin lymphomas, and the Kaposi’s sarcoma-associated virus, are both in the herpes family. The human T-lymphotropic virus, which can cause a type of leukemia, is what’s known as a retrovirus. And Merkel cell polyoma virus, which causes Merkel cell carcinoma, is in the polyoma family.

All five of these viruses contain genetic code for one or more proteins that teach cells how to avoid cell death, effectively immortalizing them and promoting cell growth. The cancer cells that develop from these oncogenic viruses all contain their original viruses’ genetic information, even when they appear years after the initial infection. But only a small percentage of people who are infected with one of these five oncogenic viruses ultimately develop the full-blown cancer associated with it.

The other two viruses, hepatitis B, in the hepadna family, and hepatitis C, in the flavi family, are somewhat different. Most people infected with those viruses are able to fight the infection through their own immunity and eliminate the virus.

However, in people who are not able to fight off the infection, long-term infections of these viruses often cause extensive liver damage. These people are at risk of developing a type of liver cancer called hepatocellular carcinoma, because the body’s attempts to repair the damaged liver tissue increase the chance of a cancer-related mutation. The viruses themselves do not teach the liver cells to become immortal or transform themselves, the way the other five oncogenic viruses do to the cells they target.

These viral-induced cancers are serious health threats. Hepatocellular carcinoma, for instance, kills approximately 800,000 people a year, making it the third-deadliest cancer globally. About three-quarters of those killed have had hepatitis virus infections in the past.

HPV is similarly dangerous. The cervical cancer it causes kills some 311,000 people a year worldwide, making it the deadliest cancer in women until recently. That number includes 36,000 women in the U.S. But HPV doesn’t just put women at risk. A similar number of people in the U.S. die each year from anal and throat cancers linked to HPV.

A schoolgirl receives the HPV vaccination.
The HPV vaccine is recommended for all children and adolescents, starting at age 11.
Peter Dazeley/The Image Bank via Getty Images

Reasons for optimism

The first viral vaccine to protect against HPV infection and its associated cancers was approved for use in the U.S. in 2006. It has proved to be highly effective at preventing both HPV infection and the subsequent development of cervical carcinoma.

HPV vaccines are now widely available around the globe. The HPV vaccine is safe, with very mild side effects. It is recommended for children starting at ages 11 to 12, since different individuals become sexually active at different ages. The protective effects of the vaccine last beyond 10 years, and booster shots are available.

Older people – typically up to 26 years of age – can also receive the HPV vaccine. By preventing infection in the first place, the vaccine also prevents the subsequent cancers that may result from a viral infection.

The vaccine for hepatitis B virus has been similarly successful over a longer time period. Introduced in 1986, it was recognized as the first anti-cancer vaccine. Since then, more than a billion people worldwide have received it. The vaccine has been shown to be extremely safe and effective.

Vaccines save lives

The numbers of cancers prevented and lives saved by the vaccines against the hepatitis B virus and human papillomavirus are enormous and indisputable. Yet, as with the resistance to COVID-19 vaccines, vaccine hesitancy is an ongoing problem. In 2019, 46% of adolescents ages 13 to 17 in the U.S. had not received their recommended HPV vaccines. In 2020 in Mississippi, HPV vaccine coverage in adolescents reached a meager 32%.

But the U.S. is better off than some other industrialized nations. In Japan, the current rate of HPV vaccine coverage in adolescents is less than 1% because of false reports of adverse events in 2013. Despite repeated, definitive discrediting of these claims, vaccine uptake in Japan has not rebounded.

Vaccination campaigns have eradicated smallpox and effectively eliminated polio, measles and certain other infectious diseases. Let’s hope that ongoing vaccine efforts can make HPV-induced cancers and hepatitis B virus-induced cancers a thing of the past as well.

Ronald C. Desrosiers, Professor of Pathology, Vice-chair for Research, University of Miami

This article is republished from The Conversation under a Creative Commons license. Read the original article.

ShareTweet
Jay K Joshi

Jay K Joshi

Dr. Jay K Joshi serves as the editor-in-chief of Daily Remedy. He is a serial entrepreneur and sought after thought-leader for matters related to healthcare innovation and medical jurisprudence. He has published articles on a variety of healthcare topics in both peer-reviewed journals and trade publications. His legal writings include amicus curiae briefs prepared for prominent federal healthcare cases.

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Videos

YouTube Video VVUxUDVQenU5RTFjUVFKNDY2ZlBmdFB3LmdVUm55WVpqRmNn This is a video about Elemental/Essential Frameworks of Healthcare Law

00:00 Elemental/Essential Frameworks of Healthcare Law
Load More... Subscribe

Expert vs. Lay Testimony

Visuals

NADAC (National Average Drug Acquisition Cost)

NADAC (National Average Drug Acquisition Cost)

by Jay K Joshi
January 29, 2023
0

We list the acquisition price of drugs that are covered under the Medicaid Drug Rebate Program - effectively, how much does the government pay for common drugs utilized by patients on Medicaid. Drugs listed are from A-CH.  

Read more

Twitter Updates

Tweets by DailyRemedy1

Newsletter

Start your Daily Remedy journey

Cultivate your knowledge of current healthcare events and ensure you receive the most accurate, insightful healthcare news and editorials.

*we hate spam as much as you do

Popular

  • Letter to the Alabama Board of Medical Examiners

    Letter to the Alabama Board of Medical Examiners

    0 shares
    Share 0 Tweet 0
  • Malicious Prosecution and Fabrication of Evidence

    0 shares
    Share 0 Tweet 0
  • Prosecuting Doctors as Drug Dealers

    0 shares
    Share 0 Tweet 0
  • My Respect for the Law

    0 shares
    Share 0 Tweet 0
  • Why Our Prescribing were for Patients’ Best Interests

    0 shares
    Share 0 Tweet 0

Daily Remedy

Daily Remedy offers the best in healthcare information and healthcare editorial content. We take pride in consistently delivering only the highest quality of insight and analysis to ensure our audience is well-informed about current healthcare topics - beyond the traditional headlines.

Daily Remedy website services, content, and products are for informational purposes only. We do not provide medical advice, diagnosis, or treatment. All rights reserved.

Important Links

  • Support Us
  • About Us
  • Contact us
  • Privacy Policy
  • Terms and Conditions

Newsletter

Start your Daily Remedy journey

Cultivate your knowledge of current healthcare events and ensure you receive the most accurate, insightful healthcare news and editorials.

*we hate spam as much as you do

  • Survey
  • Podcast
  • About Us
  • Contact us

© 2023 Daily Remedy

No Result
View All Result
  • Home
  • Articles
    • Contrarian
    • Financial Markets
    • Innovations & Investing
    • Perspectives
    • Politics & Law
    • Trends
    • Uncertainty & Complexity
  • Podcasts
  • Surveys
    • Survey Results
  • About Us
  • Contact us
  • Support Us

© 2023 Daily Remedy

Start your Daily Remedy journey

Cultivate your knowledge of current healthcare events and ensure you receive the most accurate, insightful healthcare news and editorials.

*we hate spam as much as you do