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Semaglutide and the Expansion Problem: When One Trial Becomes a Platform
Semaglutide has moved beyond its original indication and now sits at the center of a widening set of clinical questions: ...
Glucagon-Like Peptide–Based Therapies and Longevity: Clinical Implications from Emerging Evidence
Glucagon-like peptide–based therapies are increasingly used for weight management and glycemic control, but their potential impact on long-term survival remains ...
BIIB080 in Mild Alzheimer’s Disease: What a Phase 1b Exploratory Clinical Analysis Can—and Cannot—Tell Us
Can lowering tau biology translate into a clinically meaningful slowing of decline in people with early symptomatic Alzheimer’s disease? That ...
Ambient Artificial Intelligence Clinical Documentation: Workflow Support with Emerging Governance Risk
Health systems are increasingly deploying ambient artificial intelligence tools that listen to clinical encounters and automatically generate draft visit notes. ...
What the Most-Cited LLM-in-Medicine Papers Reveal—and What They Miss
In just over two years, papers on large language models (LLMs) in medicine have accumulated nearly fifteen thousand citations, creating ...
Analysis of the DHHS “Real Food” Initiative
EXECUTIVE SUMMARY The Department of Health and Human Services has launched a transformative public health initiative through the RealFood.gov platform, ...
Official MAHA Report
Explore the official MAHA Report released by the White House in May 2025.
Many famous painters struggled with mental health disorders
These include many of your favorite artists!
Romanticizing death in the age of Tuberculosis
Tuberculosis is a disease that spread widely in the 19th century. The art that stemmed from depictions of the disease ...
Semaglutide and the Expansion Problem: When One Trial Becomes a Platform
Semaglutide has moved beyond its original indication and now sits at the center of a widening set of clinical questions: cardiovascular risk, kidney disease progression, and even neurodegeneration. The question is no longer whether the drug lowers glucose or reduces weight—it does—but how far those effects extend across systems, and whether evidence from one population can be translated into another without distortion. Large, well-powered trials have produced consistent signals, yet those signals are now being applied in contexts that were...
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