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Home Uncertainty & Complexity

The Pollution and Alzheimers Connection

Correlation does not equal causation, but there's a lot of evidence.

Benjamin "Ben" Rein by Benjamin "Ben" Rein
May 8, 2024
in Uncertainty & Complexity
0
Ella Ivanescu

Ella Ivanescu

“Bad news: air pollution might literally cause Alzheimers disease… I know this probably sounds fake, but I’m a neuroscientist: let me show you.”

@dr.brein A recent study [Cho et al., 2023] links air pollution (particulate matter) to brain degeneration resembling Alzheimer’s disease… and it’s not the only study to do so. A good reminder to take care of our planet, and take care of ourselves. ________ This video was supported by the Pulitzer Center through the Truth Decay Grant Initiative, in collaboration with OpenMind Magazine. To read more about this topic, check out the accompanying article on OpenMind’s website, found in my bio 🔗. #PulitzerCenter #scicomm #neuroscience #news #pollution #alzheimers #particulatematter #science #scientist #research ♬ original sound – Dr. Ben Rein

“Bad news: air pollution might literally cause Alzheimers disease… I know this probably sounds fake, but I’m a neuroscientist: let me show you.

Earlier this year, a paper came out significant study highlighted in a renowned healthcare magazine involved brain scans of 640 people across Korea. Then they mapped everyone’s brain to their home address and compared them based on the level of air pollution where they live.

The people who were exposed to more pollution not only did worse on cognitive tests, but also, the outer layer of their brain, the cortex, was thinner. Generally, this means that brain cells are dying.

We see the same thing in Alzheimer’s, which you can see here, the outer layer looks sort of deflated because it’s thinner.

Now you might be thinking: correlation does not equal causation, and you’re right to think that. But, there is a lot more evidence. A meta-analysis including over 2.4 million people found that long term exposure to air pollution increases the risk of dementia.

This aligns with current health solutions that advocate for environmental changes to combat public health crises.

And, studies in mice have shown that air pollution can trigger brain inflammation and enhance the buildup of plaques.

The way we treat our planet affects us all, and it’s concerning at least for me, to imagine a future where we’re basically all guaranteed to get dementia because the planet is so polluted. It’s something we should be taking seriously, and in the meantime, it’s a good reason to avoid highly polluted areas. We can make ourselves more resilient through diet, exercise, and stress management. We can also protect ourselves by making a cleaner external environment.

I don’t mean to scare you, just sharing the current neuroscience that you might not have heard about, so thank you for your time, and please follow for more.

This story originally appeared on OpenMind, a digital magazine tackling science controversies and deceptions.
Source: OpenMind Magazine
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Benjamin "Ben" Rein

Benjamin "Ben" Rein

Ben Rein PhD, is a Stanford-trained neuroscientist who worked in Robert Malenka’s lab. He currently serves as the Chief Science Officer of the Mind Science Foundation.

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In this episode of the Daily Remedy Podcast, Tiffany Ryder discusses her insights on healthcare messaging, the impact of COVID-19 on patient trust, and the importance of transparency in health policy. She emphasizes the need for clear communication in the face of divisiveness and explores the complexities surrounding the estrogen debate. Additionally, Tiffany highlights positive developments in health policy and the necessity of effectively conveying these changes to the public.

Tiffany Ryder is a political commentator and public health policy thought leader who publishes the Substack newsletter Signal and Noise: https://signalandnoise.online/


Chapters

00:00 Introduction to Healthcare Conversations
02:58 Signal and Noise: Understanding Healthcare Communication
05:56 The Storytelling Problem in Healthcare
08:58 Navigating Political Divisiveness in Health Policy
11:55 The Role of Media in Health Policy
15:03 Bias in Health Reporting
17:56 Estrogen and Health Policy: A Case Study
24:00 Positive Developments in Health Policy
27:03 Looking Ahead: Future of Health Policy
31:49 Communicating Health Policy Effectively
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2027 Medicare Advantage & Part D Advance Notice

Clinical Reads

GLP-1 Drugs Have Moved Past Weight Loss. Medicine Has Not Fully Caught Up.

Glucagon-Like Peptide–Based Therapies and Longevity: Clinical Implications from Emerging Evidence

by Daily Remedy
March 1, 2026
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Glucagon-like peptide–based therapies are increasingly used for weight management and glycemic control, but their potential impact on long-term survival remains uncertain. The clinical question addressed in this report is whether treatment with glucagon-like peptide receptor agonists is associated with reductions in all-cause mortality and age-related morbidity beyond their established metabolic effects. This question matters because these agents are now prescribed across broad patient populations, including individuals without diabetes, and long-term exposure may influence cardiovascular, oncologic, and neurodegenerative outcomes. Understanding whether...

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