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    How NADAC, WAC, and ASP Shape Drug Costs

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    Public Perception of Peptide Regulation and Compounding Practices

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    How NADAC, WAC, and ASP Shape Drug Costs

    How NADAC, WAC, and ASP Shape Drug Costs

    April 20, 2026
    The Hidden Costs Employers Don’t See in Traditional Health Plans

    The Hidden Costs Employers Don’t See in Traditional Health Plans

    March 22, 2026
    The Impact of COVID-19 on Patient Trust

    The Impact of COVID-19 on Patient Trust

    March 3, 2026
    Debunking Myths About GLP-1 Medications

    Debunking Myths About GLP-1 Medications

    February 16, 2026
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    The Future of LLMs in Healthcare

    January 26, 2026
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    The Future of Healthcare Consumerism

    January 22, 2026
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    Public Perception of Peptide Regulation and Compounding Practices

    Public Perception of Peptide Regulation and Compounding Practices

    April 19, 2026
    Understanding of Clinical Evidence in Peptide and Hormone Use

    Understanding of Clinical Evidence in Peptide and Hormone Use

    March 30, 2026

    Survey Results

    Can you tell when your provider does not trust you?

    Can you tell when your provider does not trust you?

    January 18, 2026
    Do you believe national polls on health issues are accurate

    National health polls: trust in healthcare system accuracy?

    May 8, 2024
    Which health policy issues matter the most to Republican voters in the primaries?

    Which health policy issues matter the most to Republican voters in the primaries?

    May 14, 2024
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Home Uncertainty & Complexity

The Pollution and Alzheimers Connection

Correlation does not equal causation, but there's a lot of evidence.

Benjamin "Ben" Rein by Benjamin "Ben" Rein
May 8, 2024
in Uncertainty & Complexity
0
Ella Ivanescu

Ella Ivanescu

“Bad news: air pollution might literally cause Alzheimers disease… I know this probably sounds fake, but I’m a neuroscientist: let me show you.”

@dr.brein A recent study [Cho et al., 2023] links air pollution (particulate matter) to brain degeneration resembling Alzheimer’s disease… and it’s not the only study to do so. A good reminder to take care of our planet, and take care of ourselves. ________ This video was supported by the Pulitzer Center through the Truth Decay Grant Initiative, in collaboration with OpenMind Magazine. To read more about this topic, check out the accompanying article on OpenMind’s website, found in my bio 🔗. #PulitzerCenter #scicomm #neuroscience #news #pollution #alzheimers #particulatematter #science #scientist #research ♬ original sound – Dr. Ben Rein

“Bad news: air pollution might literally cause Alzheimers disease… I know this probably sounds fake, but I’m a neuroscientist: let me show you.

Earlier this year, a paper came out significant study highlighted in a renowned healthcare magazine involved brain scans of 640 people across Korea. Then they mapped everyone’s brain to their home address and compared them based on the level of air pollution where they live.

The people who were exposed to more pollution not only did worse on cognitive tests, but also, the outer layer of their brain, the cortex, was thinner. Generally, this means that brain cells are dying.

We see the same thing in Alzheimer’s, which you can see here, the outer layer looks sort of deflated because it’s thinner.

Now you might be thinking: correlation does not equal causation, and you’re right to think that. But, there is a lot more evidence. A meta-analysis including over 2.4 million people found that long term exposure to air pollution increases the risk of dementia.

This aligns with current health solutions that advocate for environmental changes to combat public health crises.

And, studies in mice have shown that air pollution can trigger brain inflammation and enhance the buildup of plaques.

The way we treat our planet affects us all, and it’s concerning at least for me, to imagine a future where we’re basically all guaranteed to get dementia because the planet is so polluted. It’s something we should be taking seriously, and in the meantime, it’s a good reason to avoid highly polluted areas. We can make ourselves more resilient through diet, exercise, and stress management. We can also protect ourselves by making a cleaner external environment.

I don’t mean to scare you, just sharing the current neuroscience that you might not have heard about, so thank you for your time, and please follow for more.

This story originally appeared on OpenMind, a digital magazine tackling science controversies and deceptions.
Source: OpenMind Magazine
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Benjamin "Ben" Rein

Benjamin "Ben" Rein

Ben Rein PhD, is a Stanford-trained neuroscientist who worked in Robert Malenka’s lab. He currently serves as the Chief Science Officer of the Mind Science Foundation.

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Videos

summary

An in-depth exploration of drug pricing, including key databases like NADAC, WAC, and ASP, and how they influence the pharmaceutical supply chain, policy, and patient advocacy. The episode also introduces MedPricer's innovative pricing intelligence platform, offering valuable insights for healthcare professionals, policymakers, and patients.

Chapters

00:00 Understanding Drug Pricing Dynamics
03:52 Exploring the Drug Pricing Database
10:07 Patient Advocacy and Drug Pricing
13:56 Market Intelligence in Drug Pricing
How NADAC, WAC, and ASP Shape Drug CostsDaily Remedy
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Policy Shift in Peptide Regulation

Clinical Reads

FDA Evaluation of Certain Bulk Drug Substances in Compounding: Clinical Interpretation

FDA Evaluation of Certain Bulk Drug Substances in Compounding: Clinical Interpretation

by Daily Remedy
April 19, 2026
0

Clinicians increasingly encounter patients using or requesting peptide-based therapies sourced through compounding pharmacies. The U.S. Food and Drug Administration has identified a subset of bulk drug substances, including certain peptides, that may present significant safety risks when used in compounded formulations. The clinical question is whether these regulatory signals reflect meaningful patient-level risk and how they should influence prescribing behavior. This matters because compounded peptides often sit outside traditional approval pathways, creating uncertainty around quality, dosing consistency, and safety. Understanding...

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