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Home Uncertainty & Complexity

The Pollution and Alzheimers Connection

Correlation does not equal causation, but there's a lot of evidence.

Benjamin "Ben" Rein by Benjamin "Ben" Rein
May 8, 2024
in Uncertainty & Complexity
0
Ella Ivanescu

Ella Ivanescu

“Bad news: air pollution might literally cause Alzheimers disease… I know this probably sounds fake, but I’m a neuroscientist: let me show you.”

@dr.brein A recent study [Cho et al., 2023] links air pollution (particulate matter) to brain degeneration resembling Alzheimer’s disease… and it’s not the only study to do so. A good reminder to take care of our planet, and take care of ourselves. ________ This video was supported by the Pulitzer Center through the Truth Decay Grant Initiative, in collaboration with OpenMind Magazine. To read more about this topic, check out the accompanying article on OpenMind’s website, found in my bio 🔗. #PulitzerCenter #scicomm #neuroscience #news #pollution #alzheimers #particulatematter #science #scientist #research ♬ original sound – Dr. Ben Rein

“Bad news: air pollution might literally cause Alzheimers disease… I know this probably sounds fake, but I’m a neuroscientist: let me show you.

Earlier this year, a paper came out significant study highlighted in a renowned healthcare magazine involved brain scans of 640 people across Korea. Then they mapped everyone’s brain to their home address and compared them based on the level of air pollution where they live.

The people who were exposed to more pollution not only did worse on cognitive tests, but also, the outer layer of their brain, the cortex, was thinner. Generally, this means that brain cells are dying.

We see the same thing in Alzheimer’s, which you can see here, the outer layer looks sort of deflated because it’s thinner.

Now you might be thinking: correlation does not equal causation, and you’re right to think that. But, there is a lot more evidence. A meta-analysis including over 2.4 million people found that long term exposure to air pollution increases the risk of dementia.

This aligns with current health solutions that advocate for environmental changes to combat public health crises.

And, studies in mice have shown that air pollution can trigger brain inflammation and enhance the buildup of plaques.

The way we treat our planet affects us all, and it’s concerning at least for me, to imagine a future where we’re basically all guaranteed to get dementia because the planet is so polluted. It’s something we should be taking seriously, and in the meantime, it’s a good reason to avoid highly polluted areas. We can make ourselves more resilient through diet, exercise, and stress management. We can also protect ourselves by making a cleaner external environment.

I don’t mean to scare you, just sharing the current neuroscience that you might not have heard about, so thank you for your time, and please follow for more.

This story originally appeared on OpenMind, a digital magazine tackling science controversies and deceptions.
Source: OpenMind Magazine
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Benjamin "Ben" Rein

Benjamin "Ben" Rein

Ben Rein PhD, is a Stanford-trained neuroscientist who worked in Robert Malenka’s lab. He currently serves as the Chief Science Officer of the Mind Science Foundation.

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In this episode, the host discusses the significance of large language models (LLMs) in healthcare, their applications, and the challenges they face. The conversation highlights the importance of simplicity in model design and the necessity of integrating patient feedback to enhance the effectiveness of LLMs in clinical settings.

Takeaways
LLMs are becoming integral in healthcare.
They can help determine costs and service options.
Hallucination in LLMs can lead to misinformation.
LLMs can produce inconsistent answers based on input.
Simplicity in LLMs is often more effective than complexity.
Patient behavior should guide LLM development.
Integrating patient feedback is crucial for accuracy.
Pre-training models with patient input enhances relevance.
Healthcare providers must understand LLM limitations.
The best LLMs will focus on patient-centered care.

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00:00 Introduction to LLMs in Healthcare
05:16 The Importance of Simplicity in LLMs
The Future of LLMs in HealthcareDaily Remedy
YouTube Video U1u-IYdpeEk
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AI Regulation and Deployment Is Now a Core Healthcare Issue

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Ambient Artificial Intelligence Clinical Documentation: Workflow Support with Emerging Governance Risk

Ambient Artificial Intelligence Clinical Documentation: Workflow Support with Emerging Governance Risk

by Daily Remedy
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Health systems are increasingly deploying ambient artificial intelligence tools that listen to clinical encounters and automatically generate draft visit notes. These systems are intended to reduce documentation burden and allow clinicians to focus more directly on patient interaction. At the same time, they raise unresolved questions about patient consent, data handling, factual accuracy, and legal responsibility for machine‑generated records. Recent policy discussions and legal actions suggest that adoption is moving faster than formal oversight frameworks. The practical clinical question is...

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