Following weeks of good news about diminishing case counts, CDC Director Rochelle P. Walensky, MD, MPH, said in a White House press briefing in early March that the country had actually recorded an increase in COVID-19 cases over the past weeks.
Walensky warned that declines in case counts and hospital admissions “may be stalling, potentially leveling off at still a very high number.”
“We at CDC consider this a very concerning shift in the trajectory,” she said.
Source: Healio
Can lowering tau biology translate into a clinically meaningful slowing of decline in people with early symptomatic Alzheimer’s disease? That is the practical question behind BIIB080, an intrathecal antisense therapy designed to reduce production of tau protein by targeting the tau gene transcript. In a phase 1b program originally designed for safety and dosing, investigators later examined cognitive, functional, and global outcomes as exploratory endpoints. The clinical question matters because current disease-modifying options primarily target amyloid, while tau pathology tracks...
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