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    How NADAC, WAC, and ASP Shape Drug Costs

    How NADAC, WAC, and ASP Shape Drug Costs

    April 20, 2026
    The Hidden Costs Employers Don’t See in Traditional Health Plans

    The Hidden Costs Employers Don’t See in Traditional Health Plans

    March 22, 2026
    The Impact of COVID-19 on Patient Trust

    The Impact of COVID-19 on Patient Trust

    March 3, 2026
    Debunking Myths About GLP-1 Medications

    Debunking Myths About GLP-1 Medications

    February 16, 2026
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    The Future of LLMs in Healthcare

    January 26, 2026
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    January 22, 2026
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    Public Perception of Peptide Regulation and Compounding Practices

    April 19, 2026
    Understanding of Clinical Evidence in Peptide and Hormone Use

    Understanding of Clinical Evidence in Peptide and Hormone Use

    March 30, 2026

    Survey Results

    Can you tell when your provider does not trust you?

    Can you tell when your provider does not trust you?

    January 18, 2026
    Do you believe national polls on health issues are accurate

    National health polls: trust in healthcare system accuracy?

    May 8, 2024
    Which health policy issues matter the most to Republican voters in the primaries?

    Which health policy issues matter the most to Republican voters in the primaries?

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Home Trends

Vaccine Hesitancy Proves Preventive Care Has Failed

Daily Remedy by Daily Remedy
February 12, 2022
in Trends
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Vaccine Hesitancy Proves Preventive Care Has Failed

Vaccine hesitancy proves that we are not ready for preventive medicine. We have our causes and effects mixed up. And the confusion is firmly entrenched in how we think. We think medicine is an effect, a response to a given cause, which we call a disease.

When we repeatedly present with high blood pressure, we are diagnosed with hypertension and given blood pressure medication. The disease, hypertension, causes us to be treated with prescription medications.

Preventive medicine requires us to think in reverse, that medicine is a cause and the prevention of disease is an effect. This is no small shift in thinking.

Imagine trying to prove that a cause is really an effect and that an effect is really a cause. It is akin to explaining to the Medieval Church that the earth revolves around the sun, not the other way around. Scientists have died trying to prove as much.

Once we acclimate to a certain way of thinking, we become set in our ways – and changing thinking is like moving mountains, nearly impossible. Just try convincing a vaccine hesitant patient to change her mind and get a COVID-19 vaccine.

Vaccine hesitant patients cannot understand why they should take medicine for a disease they may or may not get. For them, the disease is the cause, not the medicine. Persuading them that receiving medicine preemptively for a potential disease appears to them as lunacy. It simply does not make sense.

But healthcare has only itself to blame for the current state of distrust. It created this sense of cause and effect that has now indoctrinated patients.

For decades, healthcare emphasized the treatment of any and all diseases. When you present with a cough in the emergency room, you will likely receive antibiotics, regardless of whether you actually have a bacterial infection. When you present with pain, you will be asked to quantify that pain and receive treatment commensurate to the number you provide. Every disease has a defined treatment, like every cause has an effect. Eventually the thinking becomes ingrained to the point of being reflexive.

As a result, we are accustomed to treating disease with medicine. This has led to the overtreatment of patients – and explains why multi-drug resistant infections kill tens of thousands of patients annually and why we suffer the shame of rising opioid overdoses.

The overutilization of healthcare has created a dependency on treatment. This is why physicians overprescribe antibiotics and why pain management clinics are flooded with elective procedures and prescription opioids. Every cause must have an effect.

But preventive medicine requires us to break free from the cognitive shackles of such thinking. It is a paradigm shift that requires healthcare to change the causes into effects. Healthcare leaders ask this of patients when advising them to avoid unnecessary emergency department visits. Yet the same leaders who preach caution to patients will gladly schedule procedure after procedure for clinical conditions that could have been avoided by advising that same caution.

This is because caution flies in the wind when it comes to a hospital’s bottom line. As healthcare reverts to its familiar cause and effect because it is incentivized to do so.

Healthcare cannot hold one standard for the way it behaves, and then ask patients to think differently. It simply does not make sense. We cannot blame patients for adopting the thinking pervasive throughout healthcare.

Vaccine hesitancy is a phenomenon of our own creation, which we created when we prioritized treatment for disease until that thinking became cause and effect. We lauded utilization until it led to overutilization and consequently, a reactive hesitancy to vaccines among patients.

We set the thinking, so we must accept the consequences – and try to fix it.

If we have learned anything, it is that vaccine hesitancy proves healthcare must first change itself before it can ask patients to accept preventive medicine. This is the real cause and effect.

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Daily Remedy

Dr. Jay K Joshi serves as the editor-in-chief of Daily Remedy. He is a serial entrepreneur and sought after thought-leader for matters related to healthcare innovation and medical jurisprudence. He has published articles on a variety of healthcare topics in both peer-reviewed journals and trade publications. His legal writings include amicus curiae briefs prepared for prominent federal healthcare cases.

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Videos

summary

An in-depth exploration of drug pricing, including key databases like NADAC, WAC, and ASP, and how they influence the pharmaceutical supply chain, policy, and patient advocacy. The episode also introduces MedPricer's innovative pricing intelligence platform, offering valuable insights for healthcare professionals, policymakers, and patients.

Chapters

00:00 Understanding Drug Pricing Dynamics
03:52 Exploring the Drug Pricing Database
10:07 Patient Advocacy and Drug Pricing
13:56 Market Intelligence in Drug Pricing
How NADAC, WAC, and ASP Shape Drug CostsDaily Remedy
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Policy Shift in Peptide Regulation

Clinical Reads

FDA Evaluation of Certain Bulk Drug Substances in Compounding: Clinical Interpretation

FDA Evaluation of Certain Bulk Drug Substances in Compounding: Clinical Interpretation

by Daily Remedy
April 19, 2026
0

Clinicians increasingly encounter patients using or requesting peptide-based therapies sourced through compounding pharmacies. The U.S. Food and Drug Administration has identified a subset of bulk drug substances, including certain peptides, that may present significant safety risks when used in compounded formulations. The clinical question is whether these regulatory signals reflect meaningful patient-level risk and how they should influence prescribing behavior. This matters because compounded peptides often sit outside traditional approval pathways, creating uncertainty around quality, dosing consistency, and safety. Understanding...

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