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    The Future of LLMs in Healthcare

    The Future of LLMs in Healthcare

    January 26, 2026
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    The Future of Healthcare Consumerism

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    Your Body, Your Health Care: A Conversation with Dr. Jeffrey Singer

    Your Body, Your Health Care: A Conversation with Dr. Jeffrey Singer

    July 1, 2025

    The cost structure of hospitals nearly doubles

    July 1, 2025
    Navigating the Medical Licensing Maze

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    Navigating the Medical Licensing Maze

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    April 4, 2025
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    Patient Survey: Understanding Healthcare Consumerism

    January 18, 2026
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    January 3, 2026

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    Can you tell when your provider does not trust you?

    Can you tell when your provider does not trust you?

    January 18, 2026
    Do you believe national polls on health issues are accurate

    National health polls: trust in healthcare system accuracy?

    May 8, 2024
    Which health policy issues matter the most to Republican voters in the primaries?

    Which health policy issues matter the most to Republican voters in the primaries?

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Home Trends

Rise of Cash Pay Drugs

Empowering patients against soaring medication prices

Daily Remedy by Daily Remedy
May 7, 2024
in Trends
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Rise of Cash Pay Drugs

Mika Baumeister

The skyrocketing prices of prescription drugs have become a daunting reality for patients across the globe. With medication costs surpassing average household incomes, a growing number of individuals are exploring alternative ways to access essential medicines. One emerging solution gaining momentum is the rise of cash pay drugs, providing patients and physicians with a means to circumvent exorbitant price hikes and markups imposed by pharmacy benefits managers (PBMs). This modern medical approach provides a means for individuals to access essential medications outside the confines of traditional healthcare policies, empowering them to manage their healthcare needs effectively.

Understanding the Escalating Drug Pricing Crisis

The profound problem of unaffordable drugs has compelled patients and healthcare professionals to actively seek avenues to secure medications without straining their financial capacities. As prescription drug prices rise far beyond the reach of average incomes, the repercussions are undeniable, with patients being forced to forego necessary treatments or compromise on their well-being. This critical situation urgently demands sustainable solutions in healthcare policy.

Cash pay drugs represent a promising development in the quest for accessible medicines within the modern medical landscape. With direct contracting pharmacies, patients can obtain necessary prescriptions without encountering excessive price fluctuations orchestrated by PBMs. This approach eliminates intermediaries, providing patients with more control over their healthcare decisions while fostering financial transparency between them and healthcare providers in the healthcare system.

One of the key aspects of the rising popularity of cash pay drugs is the newfound collaboration between patients and physicians in modern medical practices. By working together, both parties establish the most suitable treatment plan while considering the financial capabilities of the patient. Physicians exercise their expertise in identifying alternatives or generics that provide comparable efficacy at lower costs, while patients openly communicate their concerns, enabling a more informed decision-making process in healthcare policy.

Bye-bye to Pharmacy Benefits Managers

The dominance of PBMs in determining the price of medications has been called into question. These intermediaries, acting as gatekeepers between patients and pharmacies, have often been blamed for inflating drug prices through their intricate negotiations, opaque practices, and massive profit margins. By embracing cash pay drugs, patients can bypass PBMs entirely, promoting a more transparent, affordable, and patient-oriented approach to drug procurement within the framework of healthcare policy.

Direct contracting pharmacies are at the heart of the cash pay drugs movement in modern medical practices. These pharmacies establish mutually beneficial relationships with patients, cutting out the influence of PBMs and facilitating fair, upfront pricing. By forming this direct connection, patients can access drugs at a reasonable and consistent cost, thus countering the unpredictability and arbitrary price hikes prevalent in today’s pharmaceutical market.

Cash pay drugs carry several advantages for patients within the healthcare system. First and foremost, they enable individuals to avoid lengthy insurance approvals and coverage limitations, ensuring timely access to vital medications. Moreover, patients have a clearer understanding of the costs involved, limiting surprises and allowing them to plan their finances accordingly. However, it’s crucial to acknowledge that cash pay drugs may not be suitable for everyone, particularly those who heavily rely on insurance coverage or require specialized treatments in the realm of modern medical practices.

While the emergence of cash pay drugs offers a respite from unaffordable medicine prices, it raises ethical concerns regarding equitable access to healthcare policy. Critics argue that this approach may exclude vulnerable populations with limited financial resources or those lacking insurance coverage. Consequently, policymakers and stakeholders must strive to strike a balance between facilitating patient affordability and ensuring widespread accessibility to life-saving drugs within the healthcare system.

The rise of cash pay drugs represents a compelling response to the burgeoning crisis of unaffordable medications  in modern medical practices. By enabling patients and physicians to work collaboratively, forming direct relationships with contracting pharmacies, this method grants patients greater control over their healthcare decisions while avoiding the exorbitant price hikes imposed by PBMs. Nevertheless, careful considerations must be made to not further marginalize vulnerable populations, as access to essential medications remains a fundamental human right. Ultimately, achieving a sustainable solution requires ongoing dialogue and concerted efforts from all stakeholders, driving towards an equitable healthcare system that prioritizes affordability without compromising accessibility.

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Daily Remedy

Dr. Jay K Joshi serves as the editor-in-chief of Daily Remedy. He is a serial entrepreneur and sought after thought-leader for matters related to healthcare innovation and medical jurisprudence. He has published articles on a variety of healthcare topics in both peer-reviewed journals and trade publications. His legal writings include amicus curiae briefs prepared for prominent federal healthcare cases.

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Videos

In this episode, the host discusses the significance of large language models (LLMs) in healthcare, their applications, and the challenges they face. The conversation highlights the importance of simplicity in model design and the necessity of integrating patient feedback to enhance the effectiveness of LLMs in clinical settings.

Takeaways
LLMs are becoming integral in healthcare.
They can help determine costs and service options.
Hallucination in LLMs can lead to misinformation.
LLMs can produce inconsistent answers based on input.
Simplicity in LLMs is often more effective than complexity.
Patient behavior should guide LLM development.
Integrating patient feedback is crucial for accuracy.
Pre-training models with patient input enhances relevance.
Healthcare providers must understand LLM limitations.
The best LLMs will focus on patient-centered care.

Chapters

00:00 Introduction to LLMs in Healthcare
05:16 The Importance of Simplicity in LLMs
The Future of LLMs in HealthcareDaily Remedy
YouTube Video U1u-IYdpeEk
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Large Language Models in Healthcare

Clinical Reads

What the Most-Cited LLM-in-Medicine Papers Reveal—and What They Miss

What the Most-Cited LLM-in-Medicine Papers Reveal—and What They Miss

by Daily Remedy
January 25, 2026
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In just over two years, papers on large language models (LLMs) in medicine have accumulated nearly fifteen thousand citations, creating an academic canon that is already shaping funding decisions, regulatory conversations, and clinical experimentation. This study dissects the 100 most-cited LLM-in-medicine papers to show who is driving the field, which applications dominate attention, and where the evidence remains dangerously thin. What emerges is a picture of rapid intellectual consolidation—paired with a widening gap between technical promise and clinical reality. The...

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