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Fourth large-scale COVID-19 vaccine trial begins in the United States
September 25, 2020 - 1:52 pm

A fourth Phase 3 clinical trial evaluating an investigational vaccine for coronavirus disease 2019 (COVID-19) has begun enrolling adult volunteers. The trial is designed to evaluate if the investigational Janssen COVID-19 vaccine (JNJ-78436725) can prevent symptomatic COVID-19 after a single dose regimen. Up to 60,000 volunteers will be enrolled in the trial at up to nearly 215 clinical research sites in the United States and internationally.

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The Fight Over Inoculation During the 1721 Boston Smallpox Epidemic
The Fight Over Inoculation During the 1721 Boston Smallpox Epidemic

Although inoculations were themselves a risky practice and carried a not-insignificant health risk, this data demonstrates that inoculations were significantly less fatal than the naturally occurring virus.


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