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New study finds properly analyzing vaccination efficacy against variants may require new clinical studies
April 3, 2021 - 11:00 am

Researchers at the Lindsley F. Kimball Research Institute find that as variant strains emerge, we will need to reevaluate vaccine efficacy by testing the inhibition of viral infection in vivo rather than by quantifying the antibodies produced after in vitro exposure.

Reliable proof of immunity through vaccination may only come through reinfection challenge experiments or through longitudinal studies of postvaccination subjects.

Source: Science

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The Fight Over Inoculation During the 1721 Boston Smallpox Epidemic
The Fight Over Inoculation During the 1721 Boston Smallpox Epidemic

Although inoculations were themselves a risky practice and carried a not-insignificant health risk, this data demonstrates that inoculations were significantly less fatal than the naturally occurring virus.


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