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Source: American Medical Association
What the Most-Cited LLM-in-Medicine Papers Reveal—and What They Miss
In just over two years, papers on large language models (LLMs) in medicine have accumulated nearly fifteen thousand citations, creating an academic canon that is already shaping funding decisions, regulatory conversations, and clinical experimentation. This study dissects the 100 most-cited LLM-in-medicine papers to show who is driving the field, which applications dominate attention, and where the evidence remains dangerously thin. What emerges is a picture of rapid intellectual consolidation—paired with a widening gap between technical promise and clinical reality. The...
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