Dr. Robert Califf will once again head the Food and Drug Administration, narrowly securing his position as the head of the consumer safety agency. The Senate confirmed Califf on Tuesday despite some concerns over his close ties to the pharmaceutical industry and GOP opposition to his stance on access to birth control.
The Senate voted to confirm Califf on a 50-46 vote, split largely along party lines.
Source: NPR
Semaglutide has moved beyond its original indication and now sits at the center of a widening set of clinical questions: cardiovascular risk, kidney disease progression, and even neurodegeneration. The question is no longer whether the drug lowers glucose or reduces weight—it does—but how far those effects extend across systems, and whether evidence from one population can be translated into another without distortion. Large, well-powered trials have produced consistent signals, yet those signals are now being applied in contexts that were...
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